Recent peer-reviewed publications

Correlating chemical sensitivity and basal gene expression reveals mechanism of action
Matthew G. Rees, Brinton Seashore-Ludlow, Drew J Adams, Jaime H. Cheah, Edmund V. Price1, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Munoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, Paul A. Clemons, Alykhan F. Shamji, and Stuart L. Schreiber
Nature Chemical Biology, December 2015
DOI:10.1038/nchembio.1986

Harnessing connectivity in a large-scale small-molecule sensitivity dataset
Brinton Seashore-Ludlow, Matthew G. Rees, Jaime H. Cheah, Murat Cokol, Edmund V. Price, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule1, Joshua Gould, Benjamin Alexander, Ava Li, Philip Montgomery, Mathias Wawer, Joanne D. Kotz, C. Suk-Yee Hon, Benito Munoz, Ted Liefeld, Vlado Dančík, Joshua A. Bittker, Michelle Palmer, James E. Bradner, Alykhan F. Shamji, Paul A. Clemons, and Stuart L. Schreiber
Cancer Discovery, October 2015
DOI: 10.1158/2159-8290.CD-15-0235

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes
Stuart L. Schreiber, Joanne D. Kotz, Min Li, Jeffrey Aubé, Christopher P. Austin, John C. Reed, Hugh Rosen, E. Lucile White, Larry A. Sklar, Craig W. Lindsley, Benjamin R. Alexander, Joshua Bittker, Paul A. Clemons, Andrea De Souza, Michael A. Foley, Michelle Palmer, Alykhan F. Shamji, Mathias J. Wawer, Owen McManus, Meng Wu, Beiyan Zou, Haibo Yu, Jennifer E. Golden, Frank J. Schoenen, Anton Simeonov, Ajit Jadhav, Michael R. Jackson, Anthony B. Pinkerton, Thomas D.Y. Chung, Patrick R. Griffin, Benjamin F. Cravatt, Dong-Hoon Chung, Colleen B. Jonsson, James W. Noah, William E. Severson, Subramaniam Ananthan, Bruce Edwards, Tudor I. Oprea, P. Jeffrey Conn, Corey R. Hopkins, Michael R. Wood, Shaun R. Stauffer, Kyle A. Emmitte and the NIH Molecular Libraries Project Team
Cell 161(6): 1252-1265, June 2015
DOI: 10.1016/j.cell.2015.05.023

BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
Howe, Eleanor; de Souza, Andrea; Lahr, David; Chatwin, Simon; Montgomery, Philip; Alexander, Benjamin; Nguyen, Dac-Trung; Cruz, Yasel; Stonich, Derek; Walzer, Gil; Rose, Jason; Picard, Shaita; Liu, Zihan; Rose, Jaime; Xiang, Xiaorong; Asiedu, Jacob; Durkin, Daniel; Levine, Jeri; Yang, Jeremy; Schurer, Stephan; Braisted, Johnathan; Southall, Noel; Southern, Mark; Chung, Thomas; Brudz, Stephen; Tanega, Cordelle; Schreiber, Stuart L; Bittker, Joshua; Guha, Rajarshi; Clemons, Paul
Nucleic Acids Research, 43(D1). December, 2014, NAR-02453-Data-N-2014.R2
DOI: 10.1093/nar/gku1244